Reaktion #71367

Reaktionsgleichung

6-(4-methylpiperazin-1-yl)-pyridin-3-ylamine

8-benzo[b]thiophen-3-yl-quinoxaline-5-carboxylic acid

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Title compound

8-Benzo[b]thiophen-3-yl-quinoxaline-5-carboxylic acid [6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]-amide

Lösungsmittel

DCM MeOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe title compound was prepared in analogy to the procedure

Vorschrift

The title compound was prepared in analogy to the procedure described in Step 14.1 but stirring the reaction mixture for 20 h at rt, using 6-(4-methylpiperazin-1-yl)-pyridin-3-ylamine (prepared as described in Example 33 but using N-methyl-piperazine in Step 33.2) and 8-benzo[b]thiophen-3-yl-quinoxaline-5-carboxylic acid (Example 59). Title compound: ESI-MS: 481.0 [M+H]+; tR=3.81 min (System 1); TLC: Rf=0.40 (DCM/MeOH, 9:1).

Quelle