Reaktion #712171

Reaktionsgleichung

6-(cyclopropylmethoxy)-5-(3-methoxyazetidin-1-yl)pyridine-2-carboxylic acid

1,1-dioxo-1,3-thiazolidine-4-carboxamide hydrochloride

→

title compound

Ausbeute 33.0%

3-[6-(Cyclopropylmethoxy)-5-(3-methoxyazetidin-1-yl)pyridine-2-carbonyl]-1,1-dioxo-1,3-thiazolidine-4-carboxamide

Ausbeute 33.0%

Reaktionsbedingungen

Vorschrift

In analogy to the procedure described in Example 127 e), 6-(cyclopropylmethoxy)-5-(3-methoxyazetidin-1-yl)pyridine-2-carboxylic acid (Example 128 a, 30 mg, 108 μmol) was reacted with 1,1-dioxo-1,3-thiazolidine-4-carboxamide hydrochloride (Example 127 d, 26.0 mg, 129 μmol) to give the title compound (15 mg, 33%) as off-white solid, MS (EI): m/e=425.5 [MH+].

Quelle