Reaktion #711773

ord-56dd3a7c86b04ba3b33484f107cd153c

Reaktionsgleichung

Cn1c(=O)c2c(-c3ccccc3)n(CCN)cc2n(C)c1=O
Intermediate A
Cn1c(=O)c2c(-c3ccccc3)n(CCN)cc2n(C)c1=O
6-(2-Amino-ethyl)-1,3-dimethyl-5-phenyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dione
Cc1cccc(C(=O)Cl)c1
3-methylbenzoyl chloride
→
Cc1cccc(-c2c3c(=O)n(C)c(=O)n(C)c3cn2CCN)c1
6-(2-Aminoethyl)-1,3-dimethyl-5-(m-tolyl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione

Edukte

Cn1c(=O)c2c(-c3ccccc3)n(CCN)cc2n(C)c1=O
Intermediate A
Cn1c(=O)c2c(-c3ccccc3)n(CCN)cc2n(C)c1=O
6-(2-Amino-ethyl)-1,3-dimethyl-5-phenyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dione
Cc1cccc(C(=O)Cl)c1
3-methylbenzoyl chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

This compound was prepared analogously to Intermediate A by replacing benzoyl chloride (step 2) with 3-methylbenzoyl chloride (commercial).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09303035B2uspto-grants-2016_04