Reaktion #711772

ord-7197b6a1a33844d499dd3b81e6754682

Reaktionsgleichung

Cn1c(=O)c2c(-c3ccccc3)n(CCN)cc2n(C)c1=O
Intermediate A
Cn1c(=O)c2c(-c3ccccc3)n(CCN)cc2n(C)c1=O
6-(2-Amino-ethyl)-1,3-dimethyl-5-phenyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dione
O=C(Cl)c1ccc(F)cc1
4-fluorobenzoyl chloride
→
Cn1c(=O)c2c(-c3ccc(F)cc3)n(CCN)cc2n(C)c1=O
6-(2-Amino-ethyl)-5-(4-fluoro-phenyl)-1,3-dimethyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dione

Edukte

Cn1c(=O)c2c(-c3ccccc3)n(CCN)cc2n(C)c1=O
Intermediate A
Cn1c(=O)c2c(-c3ccccc3)n(CCN)cc2n(C)c1=O
6-(2-Amino-ethyl)-1,3-dimethyl-5-phenyl-1,6-dihydro-pyrrolo[3,4-d]pyrimidine-2,4-dione
O=C(Cl)c1ccc(F)cc1
4-fluorobenzoyl chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

This compound was prepared analogously to Intermediate A by replacing benzoyl chloride (step 2) with 4-fluorobenzoyl chloride.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09303035B2uspto-grants-2016_04