Reaktion #71156

ord-89921d0387d042f6bef38b6697c319d5

Reaktionsgleichung

NC(C(=O)O)C(O)c1ccccc1
DL-3-phenylserine hydrate
O=C(O)Cc1ccccc1
phenyl-acetic acid
→
O=C(O)c1nc(Cc2ccccc2)oc1-c1ccccc1
2-Benzyl-5-phenyl-oxazole-4-carboxylic acid

Edukte

NC(C(=O)O)C(O)c1ccccc1
DL-3-phenylserine hydrate
O=C(O)Cc1ccccc1
phenyl-acetic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigePrepared

Vorschrift

Prepared starting from DL-3-phenylserine hydrate following sequentially general procedures W, X with phenyl-acetic acid, Y and Z. LC-MS-conditions 02: tR=0.95 min; [M+H]+=220.18.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08536209B2uspto-grants-2013_09