Reaktion #706328

Reaktionsgleichung

allyl bromide

ethyl salicylate

K2CO3

→

ethyl 2-(2-propenyloxy)benzoate

Ausbeute 98.3%

Lösungsmittel

DMF

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe reaction mixture was then heated on a steam bath for 2 hours
2. 2
   Sonstigethe K2CO3 was removed by filtration
3. 3
   workup.ADDITIONthe reaction mixture was poured into water
4. 4
   Extraktionextracted with ethyl acetate (3×300 ml)
5. 5
   WaschenThe organic layer was washed with brine
6. 6
   Trocknendried over MgSO4
7. 7
   Sonstigethe solvent was removed

Vorschrift

To a solution of ethyl salicylate (100 g, 0.602 mol) in DMF (400 ml) was added K2CO3 (150 g), followed by the dropwise addition of allyl bromide (87.5 g, 0.723 mol). The reaction mixture was then heated on a steam bath for 2 hours, the K2CO3 was removed by filtration and the reaction mixture was poured into water and extracted with ethyl acetate (3×300 ml). The organic layer was washed with brine, and dried over MgSO4, and the solvent was removed to afford 122 g (98%) of ethyl 2-(2-propenyloxy)benzoate.

Quelle