Reaktion #705670

ord-5cd942cc1afd49239c01cac9b90b61ca

Reaktionsgleichung

Oc1cc2ccc(Br)cc2cc1C12CC3CC(CC(C3)C1)C2
7-(1-adamantyl)-6-hydroxy-2-bromonaphthalene
Fc1ccc(CBr)cc1
4-fluorobenzyl bromide
Fc1ccc(COc2cc3ccc(Br)cc3cc2C23CC4CC(CC(C4)C2)C3)cc1
expected compound
Ausbeute 86.0%
Fc1ccc(COc2cc3ccc(Br)cc3cc2C23CC4CC(CC(C4)C2)C3)cc1
7-(1-adamantyl)-6-(4-fluorobenzyl)oxy-2-bromonaphthalene
Ausbeute 86.0%

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Following the procedure of Example 1(a), but reacting 1.1 g (3 mmol) of 7-(1-adamantyl)-6-hydroxy-2-bromonaphthalene with 420 μl (3.3 mmol) of 4-fluorobenzyl bromide, 1.2 g (86%) of the expected compound were obtained in the form of a colorless oil.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05952382uspto-grants-1999_09