Reaktion #703478

Reaktionsgleichung

potassium t-butoxide

benzyl mercaptan

hexane-1-carboxylic acid methyl ester

→

5-benzylthiomethyl-2-oxo-cyclopentanecarboxylic acid methyl ester

Ausbeute 78.0%

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe reaction product was purified by a silica gel column chromatography with ethyl acetate and n-hexane (1.5; 8.5)

Vorschrift

In accordance with the process of Example 16, potassium t-butoxide (336 mg; 3 m mol), benzyl mercaptan (372 mg; 3 m mol) and 2-oxo-bicyclo 3.1.0! hexane-1-carboxylic acid methyl ester (463 mg; 3 m mol) were used in the reaction, and the reaction product was purified by a silica gel column chromatography with ethyl acetate and n-hexane (1.5; 8.5) to obtain 650 mg of 5-benzylthiomethyl-2-oxo-cyclopentanecarboxylic acid methyl ester as an oil.

Quelle