Reaktion #70346

Reaktionsgleichung

residue

tert-butyl 2-(3′-chloro-2,4′-bipyridin-5-ylamino)-5-methylbenzoate

→

expected product

Ausbeute 62.0%

2-(3′-Chloro-2,4′-bipyridin-5-ylamino)-5-methylbenzoic acid

Ausbeute 62.0%

Lösungsmittel

trifluoroacetic acid

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solvent was evaporated
2. 2
   Sonstigethe solid residue was triturated with an isopropyl ether/hexane mixture
3. 3
   FiltrationThe solid was filtered off

Vorschrift

The solid residue obtained in step A was dissolved in 3 ml of trifluoroacetic acid and stirred for 1 hour at room temperature. The solvent was evaporated and the solid residue was triturated with an isopropyl ether/hexane mixture. The solid was filtered off affording 0.16 g (yield 62%) of the expected product.

Quelle