Reaktion #70324

ord-e2d4ee53862b43bbbe2566f95278fedb

Reaktionsgleichung

Cc1cc(N)cnc1Br
6-bromo-5-methylpyridin-3-amine
O=C(O)c1ccccc1Br
2-bromobenzoic acid
Cc1cc(Nc2ccccc2C(=O)O)cnc1Br
2-(6-Bromo-5-methylpyridin-3-ylamino)benzoic acid
Ausbeute 14.0%

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeObtained (0.17 g, yield 14%)

Vorschrift

Obtained (0.17 g, yield 14%) following the procedure described in Intermediate 13 starting with 6-bromo-5-methylpyridin-3-amine (2.70 mmol, 0.5 g) and 2-bromobenzoic acid (4.03 mmol, 0.81 g).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08536165B2uspto-grants-2013_09