Reaktion #703012

Reaktionsgleichung

diethylamine hydrochloride

orthophosphorous acid

glyoxylic acid

hydrochloric acid

→

2-diethylaminophosphonoacetic acid hydrochloride monohydrate

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturto reflux for 18 hours
2. 2
   SonstigeVolatile material is then removed by vacuum distillation
3. 3
   Sonstigethe residual oil triturated with acetone
4. 4
   Sonstigeto remove impurities

Vorschrift

A solution of 16.3 parts by weight of diethylamine hydrochloride, 16.6 parts by weight or orthophosphorous acid, and 29.6 parts by weight of glyoxylic acid (50% aqueous solution) in 50 parts by volume of 18% hydrochloric acid is heated to reflux for 18 hours. Volatile material is then removed by vacuum distillation and the residual oil triturated with acetone to remove impurities. In this way, there are obtained 28 parts by weight of 2-diethylaminophosphonoacetic acid hydrochloride monohydrate having the following analysis by weight:

Quelle