Reaktion #70042

Reaktionsgleichung

1-isocyano-2-methylpropan-2-yl methyl carbonate

1H-benzo[d]imidazol-5-amine

4-(4-hydroxypiperidin-1-yl)benzaldehyde

sodium tert.-butoxide

mono-tert-butyl malonate

→

1-(1H-Benzo[d]imidazol-5-yl)-5-(4-(4-hydroxypiperidin-1-yl)phenyl)-pyrrolidine-2,4-dione

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe compound was synthesized

Vorschrift

The compound was synthesized starting from 1H-benzo[d]imidazol-5-amine (0.970 g, 7.3 mmol), 4-(4-hydroxypiperidin-1-yl)benzaldehyde (1.5 g, 7.3 mmol), mono-tert-butyl malonate (1.17 g, 7.3 mmol), 1-isocyano-2-methylpropan-2-yl methyl carbonate (1.15 g, 7.3 mmol) and sodium tert.-butoxide (1.5 g, 14.6 mmol) according to method 5.

Quelle