Reaktion #698290

Reaktionsgleichung

N,N-Dimethyl-[5-(4-benzoylbenzoyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine

hydrogen chloride

→

desired product

N,N-dimethyl-[5-(4-benzoylbenzoyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine hydrochloride

Lösungsmittel

methanol

ethyl acetate

Reaktionsbedingungen

Aufarbeitung

1. 1
   EinengenAfter this mixture was concentrated
2. 2
   workup.ADDITIONdiethyl ether was added
3. 3
   Filtrationthe resulting solid was filtered
4. 4
   Waschenwashed with diethyl ether

Vorschrift

N,N-Dimethyl-[5-(4-benzoylbenzoyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine 0.180 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. After this mixture was concentrated, diethyl ether was added; the resulting solid was filtered and washed with diethyl ether to yield the desired product.

Quelle