Reaktion #697243

ord-c67332c98fd14ddc8679951b7b9954c5

Reaktionsgleichung

CCN1C(=O)C(C(=O)OC)c2cc(C3(C)OCCO3)ccc21
1-ethyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid methyl ester
Cc1ccc(NC(=O)c2cccc(N)c2)cc1
3-amino-N-(p-tolyl)-benzamide
→
CCN1C(=O)C(C(=O)Nc2cccc(C(=O)Nc3ccc(C)cc3)c2)c2cc(C(C)=O)ccc21
5-Acetyl-1-ethyl-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid (3-p-tolylcarbamoylphenyl)-amide

Edukte

CCN1C(=O)C(C(=O)OC)c2cc(C3(C)OCCO3)ccc21
1-ethyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid methyl ester
Cc1ccc(NC(=O)c2cccc(N)c2)cc1
3-amino-N-(p-tolyl)-benzamide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigePurified by trituration in ethyl acetate hexanes

Vorschrift

Prepared as in Example 1 from 1-ethyl-5-(2-methyl-[1,3]dioxolan-2-yl)-2-oxo-2,3-dihydro-1H-indole-3-carboxylic acid methyl ester and 3-amino-N-(p-tolyl)-benzamide. Purified by trituration in ethyl acetate hexanes. mp 168 dec.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05998463uspto-grants-1999_12