Reaktion #691937
ord-9e29f437fa32492cbe862a61782d3444
Reaktionsgleichung
pentafluorobenzenesulfonyl chloride
ammonium chloride
sodium hydroxide
→
pentafluorobenzenesulfonamide
Ausbeute 36.0%
Reagenzien
Keine
Lösungsmittel
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Aufarbeitung
- 1FiltrationThe precipitated product was filtered
- 2Sonstigerecrystallized from toluene
Vorschrift
Under room temperature, a solution of 468 g of pentafluorobenzenesulfonyl chloride in acetone was added dropwise to an aqueous solution containing 964 g of ammonium chloride, during which a pH was adjusted to 7 with an aqueous sodium hydroxide solution. The precipitated product was filtered, and recrystallized from toluene to obtain 156 g of pentafluorobenzenesulfonamide as white crystals. A structure was confirmed by 1H-NMR, 19F-NMR and IR.