Reaktion #69040

ord-bb738642139642f99f5ec83a72678cc2

Reaktionsgleichung

O=C1c2ccccc2C(=O)N1CCS(=O)(=O)Cl
2-Phthalimidoethanesulfonyl chloride
CCN1C(=O)c2ccccc2C1=O.CN[SH](=O)=O
2-phthalimidoethane N-methylsulfonamide
→
CCN1C(=O)c2ccccc2C1=O.CN(C)[SH](=O)=O
2-phthalimidoethane N,N-dimethylsulfonamide

Edukte

O=C1c2ccccc2C(=O)N1CCS(=O)(=O)Cl
2-Phthalimidoethanesulfonyl chloride
CCN1C(=O)c2ccccc2C1=O.CN[SH](=O)=O
2-phthalimidoethane N-methylsulfonamide

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

2-Phthalimidoethanesulfonyl chloride (2.0 g) was used in a procedure similar to the one used for 2-phthalimidoethane-N-methylsulfonamide. Yield: 1.03 g (45%). 1H-NMR (CDCl3) δ (ppm) 7.87-7.79 (m, 2H), 7.75-7.66 (m, 2H), 4.11 (t, J=, 2H), 3.30 (t, J=Hz, 2H), 2.87 (s, 6H).

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08530486B2uspto-grants-2013_09