Reaktion #69034

Reaktionsgleichung

2-Phthalimidoethanesulfonyl chloride

aniline

→

title compound

Ausbeute 72.5%

2-phthalimidoethane N-phenylsulfonamide

Ausbeute 72.5%

Lösungsmittel

chloroform

Reaktionsbedingungen

Aufarbeitung

1. 1
   WaschenThe organic phase was then washed with water and 1 M HCl
2. 2
   SonstigeRemoval of the solvent
3. 3
   Sonstigegave the crude product as a solid
4. 4
   Sonstigethat was recrystallised from EtOH

Vorschrift

2-Phthalimidoethanesulfonyl chloride (2.0 g) was added in portions to a solution of aniline (2.3 g) in chloroform (15 ml) and the resulting mixture was stirred at room temperature for 16 hours. The organic phase was then washed with water and 1 M HCl. Removal of the solvent gave the crude product as a solid that was recrystallised from EtOH to yield 1.76 g (65%) of the title compound as a solid. 1H-NMR (CDCl3) δ (ppm) 7.87-7.83 (m, 2H), 7.77-7.70 (m, 2H), 7.32-7.10 (m, 5H), 4.09-4.03 (m, 2H), 3.47-3.41 (m, 2H).

Quelle