Reaktion #6893

Reaktionsgleichung

(2E)-3-(4-chlorophenyl)prop-2-enoic acid

oxalyl chloride

N,N-dimethylformamide

→

(2E)-3-(4-chlorophenyl)prop-2-enoyl chloride

Lösungsmittel

methylene chloride

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe solvent was removed under vacuum
2. 2
   workup.ADDITIONThe resulting solid was diluted with hexanes
3. 3
   Sonstigethe solvent removed under vacuum
4. 4
   Sonstigeto provide an off-white solid which
5. 5
   Sonstigewas used without further purification

Vorschrift

To a solution of (2E)-3-(4-chlorophenyl)prop-2-enoic acid (2.0 g, 11 mmol) in 50 mL methylene chloride was added oxalyl chloride (1.05 mL, 12.1 mmol) and N,N-dimethylformamide (0.05 mL, 0.6 mmol). The resulting mixture was stirred at r.t. for 6 h. The solvent was removed under vacuum. The resulting solid was diluted with hexanes and the solvent removed under vacuum to provide an off-white solid which was used without further purification.

Quelle