Reaktion #684981

Reaktionsgleichung

Trifluoroacetic acid

(4-(dodecanoylsulfamoyl)benzyl)carbamic acid tert-butyl ester

→

trifluoroacetic salt

Ausbeute 128.9%

4-Aminomethyl-N-(dodecanoyl)benzenesulfonamide

Ausbeute 128.9%

Lösungsmittel

dichloromethane

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigewas at room temperature
2. 2
   SonstigeThe solvents were removed in vacuo
3. 3
   workup.DISSOLUTIONThe residue was dissolved in dichloromethane (40 ml)
4. 4
   Sonstigethe solvent was removed in vacuo

Vorschrift

Trifluoroacetic acid (25 ml) was at room temperature added to a solution of (4-(dodecanoylsulfamoyl)benzyl)carbamic acid tert-butyl ester (170 mg, 0.40 mmol) in dichloromethane (25 ml). The reaction mixture was stirred for 1 h at room temperature. The solvents were removed in vacuo. The residue was dissolved in dichloromethane (40 ml) and the solvent was removed in vacuo. The latter procedure was repeated once to give 0.19 g of the trifluoroacetic salt of 4-aminomethyl-N-(dodecanoyl)benzenesulfonamide.

Quelle