Reaktion #683881

Reaktionsgleichung

3-(4-Amino-3-nitrobenzoyl)propionic acid

sodium nitrite

potassium cyanide

→

3-(4-cyano-3-nitrobenzoyl)propionic acid

Lösungsmittel

hydrochloric acid

Reaktionsbedingungen

Vorschrift

i. 3-(4-Amino-3-nitrobenzoyl)propionic acid was diazotised in aqueous hydrochloric acid with sodium nitrite and the resultant solution treated with cuprous cyanide in potassium cyanide solution to give 3-(4-cyano-3-nitrobenzoyl)propionic acid, also available by a cyanide displacement reaction of 3-(4-fluoro-3-nitrobenzoyl)propionic acid.

Quelle