Reaktion #6827

Reaktionsgleichung

Sodium hydroxide

4-formyl-benzoic acid methyl ester

nitromethane

→

4-(2-nitro-vinyl)-benzoic acid methyl ester

Lösungsmittel

methanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigea precipitate was formed
2. 2
   SonstigeThe precipitate was isolated by filtration

Vorschrift

Sodium hydroxide (1 N, 2.3 mL) was added dropwise to 4-formyl-benzoic acid methyl ester (0.33 g) and nitromethane (0.11 ml) in 5 mL methanol at 0° C. The solution was acidified after 0.5 h and a precipitate was formed. The precipitate was isolated by filtration to give 228 mg of 4-(2-nitro-vinyl)-benzoic acid methyl ester.

Quelle