Reaktion #681622

Reaktionsgleichung

methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate

4-phenylpicolinaldehyde

→

6-(2,6-dimethoxyphenyl)-1-((4-phenylpyridin-2-yl)methyl)piperidin-2-one

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigePrepared
2. 2
   SonstigeSubsequent purification by preparative HPLC
3. 3
   Sonstigeafforded the target compound

Vorschrift

Prepared according to the described general procedure 1 (GP1) by reaction of methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate with 4-phenylpicolinaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.65 min.; [M+H]+: 403.16 g/mol.

Quelle