Reaktion #680870

ord-bcfbc4ccebc642a190d3e0fce74cf691

Reaktionsgleichung

CCS(=O)(=O)C(C)S(=O)(=O)NCc1cncc(Br)c1
N-((5-Bromopyridin-3-yl)methyl)-1-(ethylsulfonyl)ethanesulfonamide
Cn1c(B(O)O)cc2ccccc21
N-methyl-indole-2-boronic acid
→
CCS(=O)(=O)N(Cc1cncc(-c2cc3ccccc3n2C)c1)S(=O)(=O)CC
N-(ethylsulfonyl)-N-((5-(1-methyl-1H-indol-2-yl)pyridin-3-yl)methyl)ethanesulfonamide

Edukte

CCS(=O)(=O)C(C)S(=O)(=O)NCc1cncc(Br)c1
N-((5-Bromopyridin-3-yl)methyl)-1-(ethylsulfonyl)ethanesulfonamide
Cn1c(B(O)O)cc2ccccc21
N-methyl-indole-2-boronic acid

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

N-((5-Bromopyridin-3-yl)methyl)-1-(ethylsulfonyl)ethanesulfonamide and N-methyl-indole-2-boronic acid are processed according to the procedure described in Example 100 to give N-(ethylsulfonyl)-N-((5-(1-methyl-1H-indol-2-yl)pyridin-3-yl)methyl)ethanesulfonamide. MS (ESI) m/z 422.0 (M+H)+.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09242963B2uspto-grants-2016_01