Reaktion #67918

Reaktionsgleichung

4-Acetoxy-3,5-dimethoxy-benzoic acid

thionyl chloride

→

4-acetoxy-3,5-dimethoxy-benzoyl chloride

Ausbeute 102.5%

Lösungsmittel

dimethoxyethane

Reaktionsbedingungen

Vorschrift

4-Acetoxy-3,5-dimethoxy-benzoic acid (1.45 g) was heated with thionyl chloride (0.86 g) in 3 mL of dimethoxyethane. After 1.5 hours the mixture was stripped under vacuum leaving 1.60 g of 4-acetoxy-3,5-dimethoxy-benzoyl chloride as an oil. 1H NMR (CDCl3, 300 MHz) δ (ppm): 2.26 (s, 3H), 3.89 (s, 9H), 7.34 (s, 2H).

Quelle