Reaktion #678684

Reaktionsgleichung

potassium vinyltrifluoroborate

2-chloro-3,5-dimethylpyrazine

→

3,5-Dimethyl-2-vinylpyrazine

Lösungsmittel

EtOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturthe mixture was refluxed for 2 h.

Vorschrift

To a mixture of 2-chloro-3,5-dimethylpyrazine (2 g) and EtOH (20 mL) were added potassium vinyltrifluoroborate (2.067 g) and TEA (2.93 mL) at room temperature, and the mixture was stirred under nitrogen atmosphere. To the mixture was added PdCl2(dppf) (1.026 g), and the mixture was refluxed for 2 h.

Quelle