Reaktion #676371

Reaktionsgleichung

1-(5-bromopyridin-2-yl)cyclopropanamine

triethylamine

benzyl chloroformate

→

benzyl 1-(5-bromopyridin-2-yl)cyclopropylcarbamate

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeAfter work up, the crude product was purified by column chromatography on SiO2

Vorschrift

At 0° C., to the mixture of 1-(5-bromopyridin-2-yl)cyclopropanamine (1.07 g, 5.0 mmol), triethylamine (766 ul, 5.5 mmol) was added benzyl chloroformate (785 ul, 5.5 mmol). The resulting mixture was allowed to stir at it for 1 h. After work up, the crude product was purified by column chromatography on SiO2.

Quelle