Reaktion #675838

ord-05fcfa160580448a896a23f7375e8b3e

Reaktionsgleichung

OCC12CC3CC(CC(C3)C1)C2
1-adamantanemethanol
CC1(C)OB(c2cn[nH]c2)OC1(C)C
4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Cc1n[nH]c(C)c1B1OC(C)(C)C(C)(C)O1
3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
→
CC1(C)OB(c2cnn(CC34CC5CC(CC(C5)O3)C4)c2)OC1(C)C
title compound
CC1(C)OB(c2cnn(CC34CC5CC(CC(C5)O3)C4)c2)OC1(C)C
1-(2-oxatricyclo[3.3.1.13,7]dec-1-ylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Edukte

OCC12CC3CC(CC(C3)C1)C2
1-adamantanemethanol
CC1(C)OB(c2cn[nH]c2)OC1(C)C
4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
Cc1n[nH]c(C)c1B1OC(C)(C)C(C)(C)O1
3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

The title compound was prepared by substituting EXAMPLE 13A for 1-adamantanemethanol and 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole for 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole in EXAMPLE 2A.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09227963B2uspto-grants-2016_01