Reaktion #674287

ord-9fb1ff1cb2d94f1da5086a474289cc48

Reaktionsgleichung

[Ca+2].[Cl-].[Cl-]
calcium chloride
O=P([O-])([O-])O
hydrogen phosphate
[Na+].[OH-]
NaOH
→
O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].[Ca+2].[Ca+2].[Ca+2]
Calcium Phosphate

Edukte

[Ca+2].[Cl-].[Cl-]
calcium chloride
O=P([O-])([O-])O
hydrogen phosphate
[Na+].[OH-]
NaOH

Reagenzien

Keine

Lösungsmittel

O=P([O-])([O-])[O-]
phosphate

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeCaP NPs
  2. 2
    Sonstigewere obtained by filtration of the suspension through a 0.22 μm
  3. 3
    Filtrationfilter
  4. 4
    SonstigeCaP NPs
  5. 5
    Sonstigewere stored at 4° C. before use
  6. 6
    SonstigeCaP/ZOL-NPs complexes (CaPZ NPs) were prepared

Vorschrift

An aqueous solution of calcium chloride (18 mM) was added, dropwise and under magnetic stirring, to an aqueous solution on dibasic hydrogen phosphate (10.8 mM). The pH of both solutions was adjusted beforehand to 9.5 with NaOH. CaP NPs were obtained by filtration of the suspension through a 0.22 μm filter. CaP NPs were stored at 4° C. before use. CaP/ZOL-NPs complexes (CaPZ NPs) were prepared by mixing a CaP NPs dispersion with an aqueous solution of (50 mg/ml of ZOL in phosphate buffer at pH 9.5), at a volume ratio of 50:1.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US09226897B2uspto-grants-2016_01