Reaktion #67283

Reaktionsgleichung

5-bromo-3-fluoro-2-[(2R)-oxiran-2-ylmethoxyphenyl)ethanone

m-CPBA

→

5-BROMO-3-FLUORO-2-[(2R)-OXIRAN-2-YLMETHOXY]PHENYL ACETATE

Lösungsmittel

CHCl3

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigePreparation
2. 2
   TemperaturThe mixture was heated
3. 3
   Temperaturat reflux for 24 h
4. 4
   Sonstige(Preparation 25)

Vorschrift

Preparation according to Preparation 7 using 1-(5-bromo-3-fluoro-2-[(2R)-oxiran-2-ylmethoxyphenyl)ethanone (19.5 g, 67 mmol), CHCl3 and m-CPBA (77%, 60.5 g, 27 mmol). The mixture was heated at reflux for 24 h. The crude product was further used (Preparation 25). MS m/z (rel. intensity, 70 eV) 306 (M+, 4), 304 (M+, 4) 262 (bp), 69 (69), 57 (99).

Quelle