Reaktion #670108

Reaktionsgleichung

2-methylcyclohexylamine

triethylamine

compound

1-(3-chloro-4-methylbenzyl)-5-(3,4-dichlorophenyl)pyrazole-3-carboxylic acid chloride

→

expected product

N-(2-Methylcyclohex-1-yl)-1-(3-chloro-4-methylbenzyl)-5-(3,4-dichlorophenyl)pyrazole-3-carboxamide

Lösungsmittel

DCM

DCM

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThis compound is prepared by the procedure
2. 2
   SonstigeThe compound is purified by chromatography on silica using a DCM/MeOH mixture (98/2; v/v) as the eluent

Vorschrift

This compound is prepared by the procedure described in step B of EXAMPLE 36 from 1 ml of 2-methylcyclohexylamine, 1 ml of triethylamine in 15 ml of DCM and 1.5 g of the compound obtained in step A of EXAMPLE 36 in 15 ml of DCM. The compound is purified by chromatography on silica using a DCM/MeOH mixture (98/2; v/v) as the eluent to give 0.27 g of the expected product. M.p.=165° C.

Quelle