Reaktion #669761

Reaktionsgleichung

3-cyanophenyl isocyanate

4-bromoaniline

tetrahydrofuran

→

N-(3-cyanophenyl)-N'-(4-bromophenyl)urea

Ausbeute 80.5%

Lösungsmittel

chloroform

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeproduct was isolated by filtration
2. 2
   Waschenthe filtrate was washed with cold chloroform and air
3. 3
   Sonstigedried

Vorschrift

A mixture of 3-cyanophenyl isocyanate (3.76 g, 26.1 mmol) and 4-bromoaniline (4.5 g, 26.1 mmol) in 1:1 tetrahydrofuran:chloroform (100 mL). After 72 h at ambient temperature, product was isolated by filtration, the filtrate was washed with cold chloroform and air dried to give 6.6 g of N-(3-cyanophenyl)-N'-(4-bromophenyl)urea (21 mmol).

Quelle