Reaktion #66967

ord-e4e6ab946b71414a88c1b2fc8976bf13

Reaktionsgleichung

CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CBr)c1
(2′-bromomethyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester
SCc1ccccc1
benzyl mercaptan
→
CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CSCc2ccccc2)c1
(2′-Benzylsulfanylmethyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester

Edukte

CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CBr)c1
(2′-bromomethyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester
SCc1ccccc1
benzyl mercaptan

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigePrepared

Vorschrift

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-bromomethyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester and benzyl mercaptan.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08524748B2uspto-grants-2013_09