Reaktion #669669

Reaktionsgleichung

rac-3-Bromo-1-isobutyl-pyrrolidine-2-one

triphenylphosphine

→

rac-(1-Isobutyl-2-oxo-pyrrolidin-3-yl)-triphenyl-phosphonium bromide

Lösungsmittel

THF

Reaktionsbedingungen

Aufarbeitung

1. 1
   TemperaturThe mixture was then refluxed for 3 days under argon atmosphere
2. 2
   Filtrationthe suspension was filtered with suction
3. 3
   Waschenthe white crystals were washed with ice-cold THF
4. 4
   Sonstigedried under high vacuum

Vorschrift

2.74 g (12.4 mmol) rac-3-Bromo-1-isobutyl-pyrrolidine-2-one were dissolved in 12 ml THF, and 3.43 g (13.1 mmol) triphenylphosphine were added. The mixture was then refluxed for 3 days under argon atmosphere. After cooling to room temperature, the suspension was filtered with suction, the white crystals were washed with ice-cold THF and then dried under high vacuum.

Quelle