Reaktion #66933

Reaktionsgleichung

methyl 3-(benzyloxy)-5-hydroxybenzoate

Methyl 3-(benzyloxy)-5-hydroxybenzoate

potassium carbonate

iodomethane

→

methyl 3-(benzyloxy)-5-methoxybenzoate

Ausbeute 85.0%

Methyl 3-(benzyloxy)-5-methoxybenzoate

Ausbeute 85.0%

Lösungsmittel

acetone

Reaktionsbedingungen

Aufarbeitung

1. 1
   FiltrationAfter the mixture was filtered
2. 2
   Sonstigeevaporated
3. 3
   Waschenthe residue was washed with water

Vorschrift

A suspension of 4.0 g (0.0165 mmol) methyl 3-(benzyloxy)-5-hydroxybenzoate (160), 6.84 g (0.0495 mmol) potassium carbonate, and 11.71 g (0.0825 mmol) iodomethane in the 200 mL of acetone was stirred at room temperature for 24 h. After the mixture was filtered and evaporated, the residue was washed with water. The methyl 3-(benzyloxy)-5-methoxybenzoate (161) was obtained as a white solid.

Quelle