Reaktion #668986

Reaktionsgleichung

HCl

4-cyano-N-(1,1 -dimethylethoxy)carbonyl-4-(2-methylphenyl)piperidine

→

4-cyano-4-(2-methylphenyl)piperidine hydrochloride

4-Cyano-4-(2-methylphenyl)piperidine hydrochloride

Lösungsmittel

EtOAc

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeto react for 1 hour at room temperature
2. 2
   SonstigeThe EtOAc was removed in vacuo

Vorschrift

A solution of EtOAc saturated with HCl (200 ml) was added to 4-cyano-N-(1,1 -dimethylethoxy)carbonyl-4-(2-methylphenyl)piperidine (31 mg, 0.097 mmol). The resulting mixture was allowed to react for 1 hour at room temperature. The EtOAc was removed in vacuo affording 4-cyano-4-(2-methylphenyl)piperidine hydrochloride (4i) as a white solid.

Quelle