Reaktion #668809

Reaktionsgleichung

Linoleic acid

oxalyl chloride

→

linoleoyl chloride

Ausbeute 100.6%

Lösungsmittel

hexane

Reaktionsbedingungen

Aufarbeitung

1. 1
   workup.ADDITIONAfter the addition the mixture
2. 2
   Temperaturwas refluxed for 1.5 hours
3. 3
   Sonstigeevaporated under reduced pressure (60° C.; 0.5 mm Hg)

Vorschrift

Linoleic acid (100 g; purity 95%, 356 mmoles) was added dropwise over a period of 0.5 hours to a stirred mixture of oxalyl chloride (42 ml; 481 mmoles) and of hexane (120 ml) under nitrogen. After the addition the mixture was refluxed for 1.5 hours and then evaporated under reduced pressure (60° C.; 0.5 mm Hg) to give 107 grams of linoleoyl chloride as an oil.

Quelle