Reaktion #6681

Reaktionsgleichung

Cs2CO3

benzyl bromide

BzBn

ethyl 4-hydroxybenzoate

→

Ethyl 4-benzyloxybenzoate

Ausbeute 100.0%

Lösungsmittel

DMF

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigethe product was collected by extraction
2. 2
   WaschenThe organic solution was washed with brine
3. 3
   Trocknendried over MgSO4
4. 4
   SonstigeAfter evaporation of solvent
5. 5
   Sonstigepure product was obtained in yield of 100%

Vorschrift

35 mmol of benzyl bromide (BzBn, 35 mmol of ethyl 4-hydroxybenzoate (10), 14 g of Cs2CO3 and 40 ml of DMF were combined and stirred at RT ove night. Then the reaction mixture was poured into water and the product was collected by extraction. The organic solution was washed with brine and dried over MgSO4. After evaporation of solvent, pure product was obtained in yield of 100%.

Quelle