Reaktion #667697

ord-f503b39e6e1d4a8fb286936bffd064ce

Reaktionsgleichung

CC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(=O)N1CCN(c2ccccc2)CC1
2-acetyl-3-(3-nitrophenyl)-2-propenoic acid 4-phenyl-piperazide
CC(N)=C[N+](=O)[O-]
2-amino-1-nitro-1-propene
→
CC1=C(C(=O)N2CCN(c3ccccc3)CC2)C(c2cccc([N+](=O)[O-])c2)C([N+](=O)[O-])=C(C)N1
1,4-Dihydro-2,6-dimethyl-5-nitro-4-(3-nitrophenyl)pyridine-3-carboxylic acid 4-phenylpiperazide

Edukte

CC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(=O)N1CCN(c2ccccc2)CC1
2-acetyl-3-(3-nitrophenyl)-2-propenoic acid 4-phenyl-piperazide
CC(N)=C[N+](=O)[O-]
2-amino-1-nitro-1-propene

Reagenzien

Keine

Lösungsmittel

CC(C)O
isopropanol

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigeThe crude product which has precipitated out
  2. 2
    Sonstigeis crystallized from isopropanol

Vorschrift

2.5 g (10 mmol) of crude 2-acetyl-3-(3-nitrophenyl)-2-propenoic acid 4-phenyl-piperazide and 2.5 g (25 mmol) of 2-amino-1-nitro-1-propene are heated in 15 ml of isopropanol at 60° C. for 6 hours. The crude product which has precipitated out is crystallized from isopropanol.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US04753936uspto-grants-1988_06