Reaktion #6673

Reaktionsgleichung

phenothiazine

iodoethane

potassium hydroxide

→

10-Ethylphenothiazine

Lösungsmittel

toluene

Reaktionsbedingungen

Aufarbeitung

1. 1
   Temperaturwas refluxed for 24 hours
2. 2
   TemperaturAfter cooling
3. 3
   Filtrationthe reaction mixture was filtered
4. 4
   Sonstigethe solvent was evaporated
5. 5
   SonstigeThe product was crystallized from methanol

Vorschrift

A mixture of 10 g (0.05 mol) of phenothiazine, 11.7 g (0.075 mol) of iodoethane, 4.2 g (0.075 mol) of potassium hydroxide and 0.25 g of tetra-n-butylammonium hydrogen sulfate in 200 ml of dry toluene was refluxed for 24 hours. After cooling, the reaction mixture was filtered, and the solvent was evaporated. The product was crystallized from methanol. The yield of 10-ethylphenothiazine (C14H13NS, FW=227.33) was 90%.

Quelle