Reaktion #66575
ord-5da2c33f89714313b2cc2cce9bc15c35
Reaktionsgleichung
( e )
[4-chloro-2-[[(methylsulfonyl)oxy]methyl]phenoxy]-acetic Acid, 1,1-dimethylethyl Ester
( f )
[4-chloro-2-[[methyl[1-(phenylsulfonyl)-3-pyrrolidinyl]amino]methyl]phenoxy]-acetic Acid, 1,1-dimethylethyl Ester
4-methoxy-benzeneacetyl chloride
product
[4-chloro-2-[[(3S)-4-[(4-fluorophenyl)acetyl]-3-methyl-1-piperazinyl]methyl]phenoxy]-acetic Acid
→
Edukte
( e )
[4-chloro-2-[[(methylsulfonyl)oxy]methyl]phenoxy]-acetic Acid, 1,1-dimethylethyl Ester
—
( g )
( f )
[4-chloro-2-[[methyl[1-(phenylsulfonyl)-3-pyrrolidinyl]amino]methyl]phenoxy]-acetic Acid, 1,1-dimethylethyl Ester
4-methoxy-benzeneacetyl chloride
product
[4-chloro-2-[[(3S)-4-[(4-fluorophenyl)acetyl]-3-methyl-1-piperazinyl]methyl]phenoxy]-acetic Acid
Reagenzien
Keine
Reaktionsbedingungen
Detaillierte Bedingungen
See reaction.notes.procedure_details.
Vorschrift
The title compound was prepared by the methods of example 89 part (f) and example 89 part (g) using the product of example 89 part (e) and 4-methoxy-benzeneacetyl chloride.