Reaktion #66549

ord-a895ca551fd749898c5b361b4cf50be3

Reaktionsgleichung

CC1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)Cc1ccccc1
product
CC1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)Cc1ccccc1
[4-Chloro-2-[[3-methyl-4-[(phenylmethyl]sulfonyl)-1-piperazinyl]methyl]phenoxy]acetic Acid
O=C(Cl)c1ccccc1
benzoyl chloride
→
CC1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1C(=O)c1ccccc1
title compound
CC1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1C(=O)c1ccccc1
[2-[(4-Benzoyl-3-methyl-1-piperazinyl)methyl]-4-chlorophenoxy]acetic Acid

Edukte

CC1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)Cc1ccccc1
product
CC1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)Cc1ccccc1
[4-Chloro-2-[[3-methyl-4-[(phenylmethyl]sulfonyl)-1-piperazinyl]methyl]phenoxy]acetic Acid
—
( a )
O=C(Cl)c1ccccc1
benzoyl chloride

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Aufarbeitung

  1. 1
    SonstigePrepared by the method of example 30

Vorschrift

Prepared by the method of example 30, using the product from example 56 part (a) and benzoyl chloride to give the title compound.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US08524715B2uspto-grants-2013_09