Reaktion #66526

Reaktionsgleichung

1-(4-(2-chloro-4-nitrophenyl)piperazin-1-yl)-2-methylpropan-1-one

→

1-(4-(4-amino-2-chlorophenyl)piperazin-1-yl)-2-methylpropan-1-one

Ausbeute 100.0%

Lösungsmittel

EtOH

Reaktionsbedingungen

Aufarbeitung

1. 1
   EinengenThen the solution was concentrated under reduced pressure

Vorschrift

According to Scheme 4 Step 2: A solution of 1-(4-(2-chloro-4-nitrophenyl)piperazin-1-yl)-2-methylpropan-1-one (0.62 mmol, 195 mg) in EtOH (120 mL) was passed through a Pt/C 5% column in an H-Cube equipment (mode: Full). Then the solution was concentrated under reduced pressure to yield 1-(4-(4-amino-2-chlorophenyl)piperazin-1-yl)-2-methylpropan-1-one (0.62 mmol, 175 mg, 99%). The product was used without further purification.

Quelle