Reaktion #66514

Reaktionsgleichung

ethyl 3-oxopentanoate

1,1-dimethoxy-N,N-dimethylmethanamine

→

(E)-ethyl 2-((dimethylamino)methylene)-3-oxopentanoate

Ausbeute 100.0%

Lösungsmittel

DMF

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeAfter evaporation of the solvent

Vorschrift

According to Scheme 9 Step 1: A solution of ethyl 3-oxopentanoate (13.9 mmol, 2.00 g) and of 1,1-dimethoxy-N,N-dimethylmethanamine (13.9 mmole, 1.84 mL) in DMF (10 mL) was microwaved for 30 min at 120° C. After evaporation of the solvent, 2.76 g (13.9 mmol) of (E)-ethyl 2-((dimethylamino)methylene)-3-oxopentanoate were obtained and used without further purification.

Quelle