Reaktion #664469

Reaktionsgleichung

tert-butyl 4-nitro-1H-pyrazole-1-carboxylate

→

tert-butyl 4-amino-1H-pyrazole-1-carboxylate

Lösungsmittel

ethanol

Reaktionsbedingungen

Aufarbeitung

1. 1
   SonstigeThe palladium was removed by filtration
2. 2
   Sonstigethe solvent was removed in vacuo

Vorschrift

tert-butyl 4-nitro-1H-pyrazole-1-carboxylate was stirred with palladium on carbon (10%, 170 mg) in ethanol (20 mL) under an atmosphere of hydrogen at 20° C. for 18 h. The palladium was removed by filtration and the solvent was removed in vacuo to give tert-butyl 4-amino-1H-pyrazole-1-carboxylate (1.48 g). 1H NMR (d6-DMSO) δ 7.35 (d, 1H), 7.33 (d, 1H), 4.40 (s, 2H), 1.54 (s, 9H).

Quelle