Reaktion #663199

Reaktionsgleichung

butyl ethyl(3-aminopropyl)phosphinate

water

→

ethyl(3-aminopropyl)phosphinic acid

Ausbeute 98.0%

Lösungsmittel

butanol water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigeequipped with thermometer
2. 2
   Temperaturreflux condenser, high-performance stirrer
3. 3
   workup.DISTILLATIONis distilled off
4. 4
   SonstigeThe solid residue is recrystallized from acetone

Vorschrift

414 g (2 mol) of butyl ethyl(3-aminopropyl)phosphinate (produced as in Example 14) are initially charged to a 1 l five-neck flask equipped with thermometer, reflux condenser, high-performance stirrer and dropping funnel. At 160° C., during 4 h, 500 ml of water are metered in and a butanol-water mixture is distilled off. The solid residue is recrystallized from acetone to obtain 296 g (98% of theory) of ethyl(3-aminopropyl)phosphinic acid as colorless solid.

Quelle