Reaktion #6610

Reaktionsgleichung

water

4-carboxybenzyl 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl ether

potassium carbonate

iodoethane

→

title compound

Ausbeute 40.9%

4-Carbethoxybenzyl 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl ether

Ausbeute 40.9%

Lösungsmittel

butanone

Reaktionsbedingungen

Aufarbeitung

1. 1
   Extraktionextracted with ether
2. 2
   Waschenthe organic phase was washed with water
3. 3
   Trocknendried over Na2SO4
4. 4
   Einengenconcentrated
5. 5
   SonstigeRecrystallization from methanol

Vorschrift

2 g (6 mmol) of 4-carboxybenzyl 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl ether, 2.7 g (19.6 mmol) of anhydrous potassium carbonate and 19 g (12.4 mmol) of iodoethane in 18 ml of butanone were refluxed for 7 h. The mixture was then poured into water and extracted with ether, and the organic phase was washed with water, dried over Na2SO4 and concentrated. Recrystallization from methanol resulted in 0.9 g of the title compound of melting point 76°-77° C.

Quelle