Reaktion #65962

Reaktionsgleichung

1-naphthol

formalin

piperidine

morpholine

→

2-(piperidinomethyl)-1-naphthol

2-(morpholinomethyl)-1-naphthol

Reaktionsbedingungen

Vorschrift

Anon. (USA) (Res. Discl., 236, 380 (Ger), 1983) discloses a Mannich reaction of 1-naphthol with formalin and piperidine or morpholine to yield 2-(piperidinomethyl)-1-naphthol or 2-(morpholinomethyl)-1-naphthol, respectively. These compounds were subjected to hydrogenolysis (Pd/C) whereby 2-methyl-1-naphthol was produced

Quelle