Reaktion #65793

ord-00f36ee121f6420c94f2834e54e0d4f7

Reaktionsgleichung

CC(Cl)c1cc2ccccc2s1
2-(1-chloroethyl)benzo[b]thiophene
NOCc1ccccc1
O-benzylhydroxylamine
CS(C)=O
dimethyl sulphoxide
→
CC(NOCc1ccccc1)c1cc2ccccc2s1
2-(1-(benzyloxyamino)ethyl)benzo[b]thiophene

Edukte

CC(Cl)c1cc2ccccc2s1
2-(1-chloroethyl)benzo[b]thiophene
NOCc1ccccc1
O-benzylhydroxylamine
CS(C)=O
dimethyl sulphoxide

Reagenzien

Keine

Lösungsmittel

C1CCOC1
tetrahydrofuran

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

heating 2-(1-chloroethyl)benzo[b]thiophene with O-benzylhydroxylamine in a solvent such as dimethyl sulphoxide or tetrahydrofuran to give 2-(1-(benzyloxyamino)ethyl)benzo[b]thiophene of formula: ##STR4##

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05420300uspto-grants-1995_05