Reaktion #657298

Reaktionsgleichung

Potassium carbonate

Monochloroacetic acid

potassium carbonate

CO2

hydrazine hydrate

→

2,2′-(hydrazine-1,1-diyl)diacetic acid

Lösungsmittel

water

Reaktionsbedingungen

Aufarbeitung

1. 1
   Sonstigerose to 70° C
2. 2
   TemperaturThe solution was then heated until the gas evolution
3. 3
   SonstigeAt the end of the reaction
4. 4
   Sonstigethe 2,2′-(hydrazine-1,1-diyl)diacetic acid was precipitated
5. 5
   SonstigeThe product (mp 171° C.) was crystallized from water

Vorschrift

Monochloroacetic acid (2 eq.) in water was neutralized with potassium carbonate (1 eq.) followed by the addition of hydrazine hydrate (1 eq.). Potassium carbonate (1 eq.) was added to the solution gradually, whereupon, with a steady evolution of CO2, the temperature rose to 70° C. The solution was then heated until the gas evolution stopped. At the end of the reaction, the 2,2′-(hydrazine-1,1-diyl)diacetic acid was precipitated by making the solution acidic with concentrated HCl. The product (mp 171° C.) was crystallized from water, and was confirmed by NMR spectroscopy and elemental analysis.

Quelle