Reaktion #65718

ord-36d18c7a902a47f3904ccd10eb099fb4

Reaktionsgleichung

CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)OCCO3)cc1
ester
CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)OCCO3)cc1
ethyl p-(1,4-benzodioxane-6-carboxamido)benzoate
CCO.O.[K+].[OH-]
potassium hydroxide water ethanol
→
O=C(O)c1ccc(NC(=O)c2ccc3c(c2)OCCO3)cc1
p-(1,4-benzodioxane-6-carboxamido)benzoic acid

Edukte

CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)OCCO3)cc1
ester
CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)OCCO3)cc1
ethyl p-(1,4-benzodioxane-6-carboxamido)benzoate
CCO.O.[K+].[OH-]
potassium hydroxide water ethanol

Reagenzien

Keine

Reaktionsbedingungen

Detaillierte Bedingungen
See reaction.notes.procedure_details.

Vorschrift

Hydrolysis of this ester with potassium hydroxide/water/ethanol at 50° C. during 2 hours yielded p-(1,4-benzodioxane-6-carboxamido)benzoic acid, melting point 278°-280° C.

Quelle

DOI: 10.6084/m9.figshare.5104873.v1Patent: US05420273uspto-grants-1995_05